| Jack Kelly | Shae Hopkins |
| Crutchie | Sam Chung |
| Davey | Jovanny Ortiz |
| Les | Washington Chung / Matt Sherban (u/s) |
| Newsies: | |
| Albert | Noah Underhill |
| Buttons | Kaylea Kudlaty (also a Bowery Beauty) |
| Elmer | Ryan Kudlaty |
| Finch | Abby Golden (also a Bowery Beauty) |
| Ike | Emily Plato |
| Jo Jo | Brett Nickolette (also Bill) |
| Mike | Emma Lampe (also Medda Larkin) |
| Mush | Sammy Ezell |
| Race | CJ Jorgensen |
| Romeo | Nate Jorgensen |
| Specs | Juliet Kinlin |
| Splasher | Allisagrace Raynak |
| Tommy Boy | Adam Reebel (also Sietz) |
| Scabs: | Ella Hanley |
| Jillian Planisek | |
| Julia Porter | |
| Matt Sherban | |
| Kayli Vance | |
| Spot Conlon | Kameron Riggs (also a Newsie, Scab) |
| Katherine Plumber | Antonia Cangelosi |
| Darcy | Carson Strinsa (also a Goon) |
| Bill | Brett Nickolette (also a Newsie, JoJo) |
| Wiesel | Dana Hart |
| Morris Delancey | Randal Wysocky |
| Oscar Delancey | Owen Gerba |
| Goons | Aiden Pride |
| Carson Strinsa (also Darcy) | |
| Michael Ferraro (also Teddy Roosevelt) | |
| Joseph Pulitzer | Alex Aeschliman |
| Sietz | Adam Reebel (also a Newsie, Tommy Boy) |
| Bunsen | Abby Lefebvre (also A Nun & The Woman) |
| Hannah | Robin Cangelosi (also a Nun) |
| Nunzio | David Frank |
| Guard / Policeman | David Frank |
| Snyder | Bill Shaffer |
| Medda Larkin | Emma Lampe (also a Newsie, Mike (Mica)) |
| Bowery Beauties | Kaylea Kudlaty (also a Newsie – Buttons) |
| Abby Golden (also a Newsie – Finch) | |
| Stage Manager | Samantha Ksiezyk-DeCrane (also a Nun) |
| Nuns | Robin Cangelosi (also Hannah) |
| Samantha Ksiezyk-DeCrane (also The Stage Manager) | |
| Abby Lefebvre (also Bunsen & The Woman) | |
| Abby Urbaczewski (also Photographer) | |
| Photographer | Abby Urbaczewski (also a Nun) |
| Woman | Abby Lefebvre (also Bunsen and a Nun) |
| Mrs. Jacobi | Kristina Rivera |
| Mayor | Brett Hall |
| Gov. Teddy Roosevelt | Michael Ferraro (also a Goon) |
